A survey of nearly 2,500 adults in New York City, Los Angeles, and nationwide in early May 2020 found that a majority of respondents supported COVID-19 mitigation measures and adhered to public health guidelines. Widespread support of stay-at-home orders and non-essential business closures, working from home, social distancing, and limitations on gatherings was documented in all areas (67-87 percent), and most respondents reported self-isolating, keeping at least 6-feet distance from others, avoiding groups of 10 or more, and wearing face coverings in public (77-90 percent). At the time of the survey, 74.3 percent of respondents across the US said they would not feel safe if restrictions were lifted nationwide, with individuals 65+ feeling less safe than younger adults. [CDC MMWR]